Bionanotechnology is an intersection of Nanotechnology and molecular biology. It deals with Nano sized materials which are used to study biological phenomena with the nanotechnology. Nano devices, nanoparticles and nanocantilevers are the concepts that are being emerged through bionanotechnology. Peptoid nanosheets are the new tools that being developed in medical and biological fields. Peptoid nanosheet is a synthetic protein structure developed from peptoids. Due to high surface area, they serve as a platform in sensing and templating.